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DMAE can slow the rate of accumulation of lipofuscin and also speed up its removal.
DMAE and the vitamin choline have similar structures; DMAE is choline with one methyl group removed.
Both are reported to increase levels of acetylcholine in the brain, but choline must be processed in the liver first, while DMAE can be transported directly across the blood-brain barrier.
This explains why DMAE works more consistently when taken to increase concentration and short-term memory.
DMAE supplementation is best started with a small amount and increased gradually.